Motif ID: RXR{A,B,G}.p2

Z-value: 2.590


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RXRBchr6_-_33168163-0.701.9e-05Click!
RXRAchr9_+_1372183240.604.6e-04Click!
RXRGchr1_-_165414499-0.412.3e-02Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_21242592 7.313 NM_173505
ANKRD29
ankyrin repeat domain 29
chr16_-_87903028 7.081 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr9_+_131185129 6.564 CERCAM
cerebral endothelial cell adhesion molecule
chr19_-_51472003 6.197 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr16_-_85784628 6.155 NM_206967
C16orf74
chromosome 16 open reading frame 74
chr12_-_57634474 6.064 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr20_-_56284945 5.775 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr1_-_154946859 5.003 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr10_+_88718287 4.991 NM_003087
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr19_-_14228560 4.924 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr5_-_172755195 4.670 STC2
stanniocalcin 2
chr17_-_76921205 4.495 TIMP2
TIMP metallopeptidase inhibitor 2
chr6_+_43737937 4.476 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
VEGFA

















vascular endothelial growth factor A

















chr7_+_40174594 4.466 C7orf10
chromosome 7 open reading frame 10
chr1_-_154946830 4.423 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr12_-_54812936 4.392 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_-_41858948 4.364 TGFB1
transforming growth factor, beta 1
chr12_-_25055228 4.342 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr5_+_149865310 4.332 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr15_-_74494851 4.309 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr15_-_74494780 4.234 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr6_+_43738394 4.201 VEGFA
vascular endothelial growth factor A
chr19_+_54371150 4.135 MYADM
myeloid-associated differentiation marker
chr17_-_76921076 4.128 TIMP2
TIMP metallopeptidase inhibitor 2
chr1_+_32042125 4.085 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr15_-_74495093 4.045 NM_001199042
NM_022369
STRA6

stimulated by retinoic acid gene 6 homolog (mouse)

chr7_+_116166346 3.978 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr5_-_131563481 3.952 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr3_-_50340979 3.936 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr17_+_39969200 3.835 FKBP10
FK506 binding protein 10, 65 kDa
chr6_+_43738177 3.826 VEGFA
vascular endothelial growth factor A
chr17_+_39968961 3.813 NM_021939
FKBP10
FK506 binding protein 10, 65 kDa
chr7_+_40174480 3.783 NM_001193311
NM_001193312
NM_001193313
NM_024728
C7orf10



chromosome 7 open reading frame 10



chr1_-_154946801 3.780 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr17_+_39969205 3.752 FKBP10
FK506 binding protein 10, 65 kDa
chr2_-_208031570 3.751 KLF7
Kruppel-like factor 7 (ubiquitous)
chr7_-_94285477 3.667 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr7_-_27135524 3.584 NM_005522
NM_153620
HOXA1

homeobox A1

chr22_+_38035718 3.564 SH3BP1
SH3-domain binding protein 1
chr2_+_23608297 3.451 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr13_+_111138079 3.448 COL4A2
collagen, type IV, alpha 2
chr7_+_143078399 3.387 ZYX
zyxin
chr7_-_107643330 3.368 NM_002291
LAMB1
laminin, beta 1
chr1_-_153521717 3.349 NM_002960
S100A3
S100 calcium binding protein A3
chr19_-_1174263 3.339 NM_014963
SBNO2
strawberry notch homolog 2 (Drosophila)
chr20_+_42295747 3.325 MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr3_-_139258531 3.286 NM_001130992
NM_001130993
NM_002899
RBP1


retinol binding protein 1, cellular


chr10_+_17270469 3.273 VIM
vimentin
chr16_+_58497993 3.260 NM_001130487
NDRG4
NDRG family member 4
chr11_-_2162340 3.255 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr12_+_107974633 3.219 NM_001017523
BTBD11
BTB (POZ) domain containing 11
chr14_+_24867926 3.202 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr22_+_38302296 3.158 MICALL1
MICAL-like 1
chr6_+_43738757 3.157 VEGFA
vascular endothelial growth factor A
chr17_+_40811261 3.153 NM_016437
TUBG2
tubulin, gamma 2
chr5_-_172755418 3.043 STC2
stanniocalcin 2
chr7_-_94285372 3.030 SGCE
sarcoglycan, epsilon
chr2_-_10220175 3.018 CYS1
cystin 1
chr12_-_109251333 3.003 NM_001161330
NM_018984
SSH1

slingshot homolog 1 (Drosophila)

chr7_-_94285426 2.987 SGCE
sarcoglycan, epsilon
chr11_+_134123406 2.987 NM_014384
ACAD8
acyl-CoA dehydrogenase family, member 8
chr14_+_85996454 2.978 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr21_-_40685545 2.963 BRWD1
bromodomain and WD repeat domain containing 1
chr9_+_103235489 2.948 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr9_-_123639462 2.936 PHF19
PHD finger protein 19
chrX_-_106960028 2.919 TSC22D3
TSC22 domain family, member 3
chr2_-_10220321 2.913 NM_001037160
CYS1
cystin 1
chr16_+_58498182 2.913 NDRG4
NDRG family member 4
chr8_-_23177481 2.909 LOXL2
lysyl oxidase-like 2
chr2_+_239756672 2.884 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr12_-_57630867 2.883 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr9_-_123639566 2.859 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr9_+_103235634 2.856 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr17_-_76921453 2.852 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr1_-_241803203 2.850 NM_014322
OPN3
opsin 3
chr20_-_5591487 2.838 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr3_+_50306578 2.825 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr11_-_59436488 2.825 NM_152716
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr19_+_54371125 2.818 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr7_+_2671582 2.814 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr3_-_16554992 2.786 RFTN1
raftlin, lipid raft linker 1
chr6_-_32157511 2.777 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr18_+_657461 2.764 NM_001071
TYMS
thymidylate synthetase
chr7_+_143078447 2.759 ZYX
zyxin
chrX_-_49042741 2.732 NM_006150
PRICKLE3
prickle homolog 3 (Drosophila)
chr1_+_182992694 2.726


chr10_+_75910908 2.724 NM_001202450
NM_006721
ADK

adenosine kinase

chr7_+_143078444 2.724 ZYX
zyxin
chr1_-_6545521 2.721 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr10_+_17270257 2.713 NM_003380
VIM
vimentin
chrX_-_51239426 2.697 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr16_+_30194925 2.674 CORO1A
coronin, actin binding protein, 1A
chr19_+_676346 2.668 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr2_-_26205437 2.664 NM_002254
KIF3C
kinesin family member 3C
chr7_+_2671630 2.663 TTYH3
tweety homolog 3 (Drosophila)
chr22_+_38035683 2.644 NM_018957
SH3BP1
SH3-domain binding protein 1
chr9_+_116638544 2.624 NM_133374
ZNF618
zinc finger protein 618
chr15_+_69706619 2.617 NM_004856
NM_138555
KIF23

kinesin family member 23

chr8_+_26371461 2.614 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr18_+_657633 2.605 TYMS
thymidylate synthetase
chr7_+_143078395 2.601 ZYX
zyxin
chr12_-_53625834 2.594 NM_000966
NM_001243730
NM_001243731
RARG


retinoic acid receptor, gamma


chr21_-_46707748 2.580 NM_015227
NM_133635
POFUT2

protein O-fucosyltransferase 2

chr7_+_143078608 2.571 ZYX
zyxin
chr19_-_1174257 2.563 SBNO2
strawberry notch homolog 2 (Drosophila)
chr19_+_54371170 2.555 MYADM
myeloid-associated differentiation marker
chr15_-_81616439 2.550 NM_181900
STARD5
StAR-related lipid transfer (START) domain containing 5
chr17_+_1958354 2.535 NM_006497
HIC1
hypermethylated in cancer 1
chr11_+_65405538 2.531 NM_006747
SIPA1
signal-induced proliferation-associated 1
chr20_-_36793646 2.517 NM_004613
NM_198951
TGM2

transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

chr20_+_56285213 2.511


chr1_+_32042122 2.505 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_-_155881063 2.498 RIT1
Ras-like without CAAX 1
chr3_+_50192847 2.485 NM_004186
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr12_-_89746238 2.483 DUSP6
dual specificity phosphatase 6
chr12_-_52585686 2.480 NM_001081492
NM_182507
KRT80

keratin 80

chr20_+_25228698 2.463 NM_002862
PYGB
phosphorylase, glycogen; brain
chr11_-_59436366 2.457 PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr1_+_32042085 2.449 NM_001204414
NM_022164
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr5_-_157002739 2.445 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chrX_-_49042845 2.428 PRICKLE3
prickle homolog 3 (Drosophila)
chr17_+_7210841 2.384 NM_001970
EIF5A
eukaryotic translation initiation factor 5A
chrX_-_106959597 2.370 NM_001015881
TSC22D3
TSC22 domain family, member 3
chrX_+_135229536 2.355 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr1_-_150693321 2.308 NM_001199829
NM_032132
HORMAD1

HORMA domain containing 1

chr2_-_26205327 2.295 KIF3C
kinesin family member 3C
chr5_+_126112847 2.272 LMNB1
lamin B1
chr20_-_44539542 2.269 PLTP
phospholipid transfer protein
chr20_+_42295708 2.269 NM_002466
MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr11_+_450346 2.265 PTDSS2
phosphatidylserine synthase 2
chr2_-_75788079 2.260 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr17_-_41622727 2.258 ETV4
ets variant 4
chr19_-_4723814 2.257 NM_139159
DPP9
dipeptidyl-peptidase 9
chrX_-_51239295 2.256 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_-_50143350 2.237 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr11_-_87908551 2.222 NM_022337
RAB38
RAB38, member RAS oncogene family
chr11_+_450260 2.222 NM_030783
PTDSS2
phosphatidylserine synthase 2
chr19_-_47354060 2.209 NM_004069
NM_021575
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chr19_-_46148606 2.197 NM_001193268
EML2
echinoderm microtubule associated protein like 2
chr7_+_143078457 2.196 ZYX
zyxin
chr13_-_52027133 2.180 INTS6
integrator complex subunit 6
chr12_-_89745997 2.173 DUSP6
dual specificity phosphatase 6
chr18_+_657674 2.166 TYMS
thymidylate synthetase
chr17_+_7210929 2.164 EIF5A
eukaryotic translation initiation factor 5A
chr19_-_51504799 2.161 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr19_-_1174201 2.156


chr20_-_44539597 2.151 NM_001242921
PLTP
phospholipid transfer protein
chr15_+_39873276 2.142 NM_003246
THBS1
thrombospondin 1
chr15_-_78423556 2.133 NM_006383
CIB2
calcium and integrin binding family member 2
chr10_+_11784355 2.125 NM_024693
ECHDC3
enoyl CoA hydratase domain containing 3
chr12_-_89746244 2.118 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr6_-_2971281 2.108 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr5_+_126112819 2.098 NM_001198557
LMNB1
lamin B1
chr7_+_143078358 2.097 NM_001010972
NM_003461
ZYX

zyxin

chr6_-_30652434 2.094 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr1_+_26606621 2.085 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_46768973 2.078


chr2_-_75788027 2.069 FAM176A
family with sequence similarity 176, member A
chr5_-_149682447 2.066 NM_001012301
ARSI
arylsulfatase family, member I
chr22_+_44319685 2.064 PNPLA3
patatin-like phospholipase domain containing 3
chr22_+_46692637 2.039 NM_016426
GTSE1
G-2 and S-phase expressed 1
chr13_+_110959592 2.034 NM_001846
COL4A2
collagen, type IV, alpha 2
chr22_+_31489343 2.033 SMTN
smoothelin
chr19_-_4723755 2.030 DPP9
dipeptidyl-peptidase 9
chr19_-_4723791 2.012 DPP9
dipeptidyl-peptidase 9
chr1_+_230202966 1.999 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr19_+_6361462 1.974 NM_006012
CLPP
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)
chr20_-_56285576 1.970 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr12_-_109251271 1.970 SSH1
slingshot homolog 1 (Drosophila)
chrX_+_51075667 1.966 NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr17_-_41174431 1.960 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr2_-_72374919 1.944 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr19_-_14228362 1.940 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr3_-_59035700 1.930 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr20_-_25566137 1.926 NM_025176
NINL
ninein-like
chr1_+_32687970 1.917 NM_003757
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr21_+_40177847 1.916 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr1_+_230202928 1.908 NM_004481
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr14_+_75745480 1.906 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_+_6052699 1.902 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr17_-_39211462 1.893 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr17_-_41174402 1.892 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr17_-_41174327 1.887 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr3_-_48672807 1.885 SLC26A6
solute carrier family 26, member 6
chr22_+_44319618 1.878 NM_025225
PNPLA3
patatin-like phospholipase domain containing 3
chr1_-_109825683 1.877 PSRC1
proline/serine-rich coiled-coil 1
chr7_+_30067942 1.871 NM_001197026
NM_001197027
NM_032639
PLEKHA8


pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8


chr14_+_23305913 1.868 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr7_-_767286 1.857 NM_001164758
NM_001164759
PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

chr10_+_102106958 1.855 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr14_-_23834417 1.849 EFS
embryonal Fyn-associated substrate
chr11_-_568419 1.848 MIR210HG
MIR210 host gene (non-protein coding)
chr17_-_39968450 1.833 NM_006455
LEPREL4
leprecan-like 4
chr22_+_44319674 1.830 PNPLA3
patatin-like phospholipase domain containing 3
chr17_-_40575117 1.827 NM_012232
PTRF
polymerase I and transcript release factor
chr6_-_2971787 1.826 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr7_+_100136784 1.802 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr2_-_27718059 1.800 FNDC4
fibronectin type III domain containing 4
chr22_+_50624353 1.792 NM_025204
TRABD
TraB domain containing
chr19_+_6361558 1.790 CLPP
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 3.77e-14 GO:0009987 cellular process
1.17 1.15e-08 GO:0065007 biological regulation
1.28 8.82e-08 GO:0023052 signaling
1.17 1.01e-07 GO:0050789 regulation of biological process
1.17 1.74e-07 GO:0050794 regulation of cellular process
1.29 2.05e-07 GO:0007165 signal transduction
1.39 1.88e-06 GO:0048583 regulation of response to stimulus
1.46 2.32e-06 GO:0009966 regulation of signal transduction
1.43 6.86e-06 GO:0009653 anatomical structure morphogenesis
1.41 7.47e-06 GO:0023051 regulation of signaling
1.23 1.22e-05 GO:0051716 cellular response to stimulus
1.59 1.23e-05 GO:0051128 regulation of cellular component organization
1.96 1.50e-05 GO:0007411 axon guidance
1.25 3.70e-05 GO:0016043 cellular component organization
1.43 4.55e-05 GO:0035556 intracellular signal transduction
1.29 6.15e-05 GO:0048518 positive regulation of biological process
1.30 6.74e-05 GO:0048522 positive regulation of cellular process
1.91 6.95e-05 GO:0032535 regulation of cellular component size
2.08 1.43e-04 GO:0051129 negative regulation of cellular component organization
1.32 3.14e-04 GO:0030154 cell differentiation
1.23 5.71e-04 GO:0071840 cellular component organization or biogenesis
1.47 7.80e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.78 8.80e-04 GO:0090066 regulation of anatomical structure size
1.83 9.65e-04 GO:0033043 regulation of organelle organization
1.66 1.26e-03 GO:0000904 cell morphogenesis involved in differentiation
2.97 1.37e-03 GO:0008064 regulation of actin polymerization or depolymerization
1.70 1.49e-03 GO:0048812 neuron projection morphogenesis
1.43 1.50e-03 GO:0010646 regulation of cell communication
1.29 2.11e-03 GO:0048869 cellular developmental process
1.69 2.62e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.88 2.64e-03 GO:0030832 regulation of actin filament length
1.65 3.10e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.55 3.10e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.63 3.58e-03 GO:0009967 positive regulation of signal transduction
1.69 4.12e-03 GO:0007409 axonogenesis
1.21 4.62e-03 GO:0051179 localization
1.43 4.81e-03 GO:0009605 response to external stimulus
1.63 5.00e-03 GO:0031175 neuron projection development
1.46 5.12e-03 GO:0048699 generation of neurons
1.45 5.48e-03 GO:0022008 neurogenesis
1.70 5.85e-03 GO:0010627 regulation of intracellular protein kinase cascade
1.59 6.65e-03 GO:0023056 positive regulation of signaling
1.56 6.90e-03 GO:0000902 cell morphogenesis
2.67 7.55e-03 GO:0032271 regulation of protein polymerization
1.41 7.74e-03 GO:0032268 regulation of cellular protein metabolic process
1.26 7.78e-03 GO:0048519 negative regulation of biological process
1.43 9.01e-03 GO:0048468 cell development
1.59 9.48e-03 GO:0006935 chemotaxis
1.59 9.48e-03 GO:0042330 taxis
2.17 1.11e-02 GO:0050678 regulation of epithelial cell proliferation
1.97 1.13e-02 GO:0044087 regulation of cellular component biogenesis
1.68 1.14e-02 GO:0007264 small GTPase mediated signal transduction
1.80 1.31e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.52 1.32e-02 GO:0001932 regulation of protein phosphorylation
1.70 1.45e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.47 1.54e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 1.57e-02 GO:0051246 regulation of protein metabolic process
1.57 1.61e-02 GO:0010647 positive regulation of cell communication
1.63 1.61e-02 GO:0032583 regulation of gene-specific transcription
1.46 1.71e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.21 1.91e-02 GO:0048856 anatomical structure development
1.49 1.95e-02 GO:0010628 positive regulation of gene expression
1.49 1.95e-02 GO:0042325 regulation of phosphorylation
1.26 2.00e-02 GO:0048523 negative regulation of cellular process
1.36 2.09e-02 GO:0031325 positive regulation of cellular metabolic process
1.42 2.19e-02 GO:0050793 regulation of developmental process
1.22 2.24e-02 GO:0048731 system development
1.77 2.45e-02 GO:0051270 regulation of cellular component movement
1.18 2.47e-02 GO:0032502 developmental process
1.19 2.49e-02 GO:0031323 regulation of cellular metabolic process
1.49 2.67e-02 GO:0045595 regulation of cell differentiation
1.46 2.73e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.51 2.73e-02 GO:0032989 cellular component morphogenesis
1.51 2.83e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.48 2.89e-02 GO:0019220 regulation of phosphate metabolic process
1.48 2.89e-02 GO:0051174 regulation of phosphorus metabolic process
2.83 2.98e-02 GO:0030833 regulation of actin filament polymerization
1.13 3.20e-02 GO:0044237 cellular metabolic process
1.56 3.49e-02 GO:0048858 cell projection morphogenesis
1.43 3.71e-02 GO:0048584 positive regulation of response to stimulus
2.30 3.83e-02 GO:0032956 regulation of actin cytoskeleton organization
1.22 3.85e-02 GO:0071842 cellular component organization at cellular level
1.35 3.97e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.78 4.05e-02 GO:0050680 negative regulation of epithelial cell proliferation
1.19 4.22e-02 GO:0080090 regulation of primary metabolic process
2.18 4.32e-02 GO:0043254 regulation of protein complex assembly
1.55 4.97e-02 GO:0032990 cell part morphogenesis
2.14 5.00e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 6.34e-06 GO:0005737 cytoplasm
1.28 4.78e-04 GO:0005829 cytosol
1.13 2.30e-03 GO:0044444 cytoplasmic part
1.07 2.91e-03 GO:0044424 intracellular part
1.07 3.66e-03 GO:0005622 intracellular
2.60 4.80e-03 GO:0005604 basement membrane
1.69 1.31e-02 GO:0015629 actin cytoskeleton
2.05 1.43e-02 GO:0005938 cell cortex
1.86 2.42e-02 GO:0031252 cell leading edge
2.10 2.62e-02 GO:0044420 extracellular matrix part
1.32 3.35e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 2.46e-10 GO:0005515 protein binding
1.53 2.68e-03 GO:0005198 structural molecule activity
2.57 2.70e-03 GO:0005201 extracellular matrix structural constituent
1.06 1.42e-02 GO:0005488 binding
1.34 4.97e-02 GO:0030528 transcription regulator activity